How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin Proteolytic processing of lysyl oxidaselike 2 in the extracellular matrix is required for crosslinking of basement membrane collagen IV Journal of Biological Chemistry Emerging Roles of Lysyl Oxidases in the Cardiovascular System: New Concepts and Therapeutic Challenges Lysyl oxidase (LOX) mediates intermolecular crosslinks between Download Scientific Diagram Human lysyl oxidase like 2 ScienceDirect Site specific cross linking of collagen peptides by lysyl advanced glycation endproducts Chemical Communications (RSC Publishing)