Tylenol, Autism, And The Glutathione Connection OC Integrative Medicine Since Tylenol is such a hot topic right now, did you know it depletes glutathione levels? When your body processes Tylenol in the liver, one of the pathways creates a toxic byproduct. To neutralize Acetaminophen Anesthesia Key Does Acetaminophen Deplete Glutathione? Understanding the Connection Cymbiotika CYMBIOTIKA Can Tylenol (acetaminophen) deplete glutathione levels in the body? Acetaminophen Pathway (toxic doses), Pharmacokinetics